The Interaction of Aluminum Oxide Nanopowder With Cells

aluminium oxide nanopowder srl is an inorganic compound with the formula Al2O3. It is a dark brown crystalline mineral, also known as corundum or aluminium alumina. It is the primary component of alumina, which in turn is the main constituent of many different ceramics. Aluminium oxide is a common ingredient in industrial applications such as catalysts, adsorbents, and additives for concrete mixtures, tribological additives for lubricating liquids, raw materials for ceramic production, as well as in cosmetics and textiles.

Aluminum oxide nanopowder has been shown to have bacteriostatic activity against some strains of bacteria in vitro, with the effect being characterized by the retardation of colony growth and an increase in inhibition zones. These properties have led to a search for new antibacterial agents in light of the growing number of antibiotic resistant strains.

Although aluminium oxide nanopowders exhibit low toxicity to eukaryotic cells, they may nevertheless induce oxidative stress in the cells of animals that are exposed to them. Therefore, the use of these particles in biomedical applications requires a more detailed study of their mechanisms of interaction with cellular systems.

In order to investigate the interaction between NMs and components of the physiological medium, several techniques were used, including SAXS, TEM in element resolved mode, and IBM. In addition, the morphological characteristics of the NMs were investigated using ToF-SIMS. NMs with a larger surface area were found to be taken up more readily than those with a smaller one.

Newsletter Updates

Enter your email address below and subscribe to our newsletter